Effect of fibrin vs cellulose based haemostatic agents withtraditional haemostatic procedures in thyroid surgery | Karanikolic | Pakistan Journal of Medical Sciences
 
میز اداری صندلی مدیریتی صندلی اداری تبلیغات کلیکی میز تلویزیون پاراگلایدر آگهی رایگان محسن چاوشی مسیح و آرش آهنگ جدید لباس زیر شورت زنانه خرید اینترنتی وبلاگدهی گن لاغری

Effect of fibrin vs cellulose based haemostatic agents withtraditional haemostatic procedures in thyroid surgery

Aleksandar Karanikolic, Miodrag Djordjevic, Nebojsa Djordjevic, Ilija Golubovic

Abstract


Objective: To compare the efficacy of fibrin-based hemostat and cellulose-based hemostat with traditional procedures in patients undergoing thyroid surgery.

Methods: Between January 2012 and December 2016, 255 patients were scheduled to undergo total thyroidectomy at Surgical Clinic Nis. The patients were randomized to: Group-I use of classic surgical procedures to achieve hemostasis, Group-II use Surgicel and Group-III use Beriplas.

Results: A statistically significant reduction of surgical time was found for Group-I compared with Group-II and III (p≤0.01 for both groups). Statistically significant reduction of intraoperative blood loss was found for Group-I compared with Group-II from 102.3mL vs. 86.1mL (p≤0.01) as well as compared to Group-III (mean 77.4mL, p≤0.01). Removal of the wound drain occurred sooner in the Group-II and III compared with Group-I (mean 37.1h vs. 40.1h, p≤0.05; mean 31.2h vs. 40.1h, p≤0.01). There were no significant differences in terms of postoperative morbidity among the groups.

Conclusions: Fibrin based haemostat seems to be an effective hemostatic agent for patients undergoing thyroid surgery. We suggest that, where appropriate, this fibrin-based haemostat should be used as a first line hemostatic agent in thyroidectomy in combination with conventional surgical means of hemostasis.

doi: https://doi.org/10.12669/pjms.336.13692

How to cite this:Aleksandar K, Miodagl D, Nebojsa D, Ilija G. Effect of fibrin vs cellulose based haemostatic agents with traditional haemostatic procedures in thyroid surgery. Pak J Med Sci. 2017;33(6):1360-1365.   doi: https://doi.org/10.12669/pjms.336.13692

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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