Hereditary angioedema a rare cause of recurrent abdominal pain

Abstract

Hereditary angioedema is a rare autosomal dominant inherited disease which is characterized by an episodic, self-limiting increase in vascular permeability. Symptoms commonly involve in nonpitting, nonpruritic skin swellings. We present a case of hereditary angioedema. The patinets complained of  a recurrent abdominal pain without accompanying skin swelling whose diagnosis was delayed nearly 20 years and accepted an unnecessary surgery. According to the decreased serum C1-inhibitor and C4 concentration, the patient was finally diagnosed with hereditary angioedema type I. After treatment  with danazole, the patient reported a significant decrease in the frequency of attacks and the severity of pain. HAE is a rare cause of abdominal pain, however it needs to be taken as one of the differential diagnosis of various acute abdomens in order to avoid unnecessary surgeries.

doi: http://dx.doi.org/10.12669/pjms.305.5524

How to cite this:Chen X, Yang YX, Liu YL, Gan HT, Wen ZH. Hereditary angioedema a rare cause of recurrent abdominal pain. Pak J Med Sci 2014;30(5):1147-1149.   doi: http://dx.doi.org/10.12669/pjms.305.5524

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