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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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Volume 22 |
April - June 2006 |
Number 2 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE- |
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Volume 22 |
April - June 2006 |
Number 2 |
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Silent Myocardial Ischemia and Microalbuminuria in
Asymptomatic Type-2 Diabetic PatientsAbdul Zahrah F. Hussein, Sarkis K. Strak
ABSTRACT
Objectives: To detect silent myocardial ischemia (SMI) in asymptomatic type 2 diabetic patients with or without microalbuminuria, and the importance of microalbuminuria as a predictor for diabetic cardiovascular complications.
Methods: Sixty asymptomatic patients with type 2 diabetes were included in this study. Thirty (17 males, 13 females) with mean age of 54±8.3 years had microalbuminuria (Group-I) were compared with another thirty (21 males and 9 females) with a mean age of (52±7.8 years) who had normoalbuminuria (Group-II). A maximum symptom-limited treadmill exercise test was used to detect silent ischemia.
Results: In Group-I, 9 patients (30%) had SMI, with 6 patients showing SMI at higher work load and 3 at low work load. In Group-II, 2 patients (6.6%) showed SMI, one at high load and another at low load.
Conclusions: The prevalence of SMI in asymptomatic microalbuminuric and normalbuminuric type 2 diabetic patients were 30% and 6.6% respectively. Even with a maximum exercise, myocardial ischemia might be completely asymptomatic in type 2 diabetic patients.
Key words: Type 2 diabetic mellitus, silent myocardial ischemia, treadmill exercise test.
Pak J Med Sci April - June 2006 Vol. 22 No. 2 116 - 121
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