Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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Short Communication

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Volume 22

April - June 2006

Number 2


 

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Concomitant use of insulin glargine and
NPH in type-1 diabetes

Abdulrahman Al shaikh

ABSTRACT

In this prospective study on 13 patients with type 1 diabetes we evaluated the glycemic control and hypoglycemic episodes on a combination therapy of NPH and glargine insulin. Glycosylated hemoglobin (HbA1C), fasting (FPG), Post Prandial glucose (PPG), and blood glucose on arrival from the school levels were recorded at baseline and two monthly intervals for 6 months. The mean HbA1C reduced from 9.7 to 7.1%, incidence of hypoglycemia reduced from 1.8 to 1.2, mean Fasting Blood Glucose (FBG) from 121to 108 mg/dl and mean blood glucose on arrival from the school from 287.6 to 167.3 mg/dl over 6 months observation period. This regimen helps us to ovoid hyperglycemia on arrival from the school with no increase in hypoglycemic events.

Key words: Glycosylated hemoglobin, Type 1 diabetes, Insulin glargine.

Pak J Med Sci April - June 2006 Vol. 22 No. 2 208 - 210


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