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CASE REPORT |
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Volume 23 |
April - June 2007 (Part-I) |
Number 2 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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CASE REPORT |
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Volume 23 |
April - June 2007 (Part-I) |
Number 2 |
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Effect of Sildenafil in Primary
Pulmonary Hypertension
Saleem Sharieff1ABSTRACT
Primary pulmonary hypertension is a disorder with limited treatment options and poor outcome. We demonstrated a beneficial role of sildenafil, a phosphodiesterase 5 inhibitor, in a patient with primary pulmonary hypertension. After the initiation of sildenafil the pulmonary artery pressure decreased from 40/20mmHg to 16/6mmHg, while mean pulmonary arterial systolic pressure decreased from 25mmHg to 10mmHg. Sildenafil has a beneficial effect in patients with primary pulmonary hypertension in improving the functional class and decreasing the pulmonary artery pressures.
KEY WORDS: Sildenafil, Pulmonary Hypertension, Effectiveness.
Pak J Med Sci April 2007 Vol. 23 No. 2 264-266
1. Dr. Saleem Sharieff FCPS, FRCP(C)
Cardiology Section,
Department of Medicine,
Sultan Qaboos University Hospital,
Al-Khod-123,
Muscat – Oman.
Correspondence:
Dr. Saleem Sharieff FCPS, FRCP(C)
Grand River Hospital, Dept. of Medicine,
835 King Street West, Kitchener, ON.
N2G 1G3,Canada.
E-mail: saleem_sharieff@hotmail.com
* Received for Publication: January 18, 2007
* Accepted: March 11, 2007
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