Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 24

April - June 2008 (Part-I)

Number  2


 

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Antibiotic sensitivity pattern of
staphylococcus aureus
in Abakaliki, Nigeria

Ikeagwu IJ1, Amadi ES2, Iroha IR3

ABSTRACT

Objective: To investigate the sensitivity pattern of Staphylococcus aureus isolates obtained from clinical specimens including urine, wound, high vaginal swab and semen to commonly used antibiotics.

Methodology: The susceptibility patterns of these isolates were determined using the disc diffusion and agar well diffusion methods.

Results: Out of 174 samples, 51 (29.2%) yielded S. aureus with the highest isolation from semen (66.7%) and the least from urine (15.6%). Following the disc diffusion, the highest sensitivity was recorded for Ofloxacin (65%) while the least was for Co-trimoxazole (6%). Amoxicillin, Ampicillin, Tetracycline and Cloxacillin recorded 37%, 19%, 8% and 11% respectively. Also, following the agar well diffusion method, the highest sensitivity was recorded for Ofloxacin (65%) and the least for Co-trimoxazole (8%). The other drugs recorded the following readings; Amoxycillin (37%), Ampicillin (21%), Tetracycline (23%) and Cloxacillin (13%).

Conclusions: The study recommends the use of Ofloxacin in the treatment of S. aureus infections in the study area. It also underscores the need for sensitivity testing before the administration of antibiotics for the treatment of Staphylococcal infections.

KEY WORDS: Antibiotics, Abakaliki, Sensitivity, Resistance, Staphylococcus Aureus.

Pak J Med Sci    April - June 2008 (Part-I)    Vol. 24 No. 2    231-235


1. Ikeagwu IJ, PGD
Department of Medical Microbiology,
Federal Medical Centre,
Abakaliki, Ebonyi State,
Nigeria.
2. Amadi ES, Ph.D
3. Iroha IR, Ph.D
2-3: Department of Applied Microbiology,
Faculty of Applied and Natural Sciences,
Ebonyi State University,
PMB 053 Abakaliki, Ebonyi State, Nigeria.

Correspondence:

Dr. Amadi ES,
Department of Applied Microbiology,
Faculty of Applied and Natural Sciences,
Ebonyi State University,
PMB 053 Abakaliki, Ebonyi State, Nigeria.
E-mail: amadies2001@yahoo.com

* Received for Publication: October 6, 2007
* Accepted for Publication: February 8, 2008



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