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Volume 25 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 25 |
April - June 2009 (Part-I) |
Number 2 |
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Neonatal Septicemia in
Gaza City Hospitals
Abed El Hakeem Noman El Jadba1, Mansour Sobhi El Yazji2
ABSTRACT
Objective: To determine the most common pathogens and antimicrobial sensitivity of neonatal septicemia in Neonatal Intensive Care Units (NICU) in Gaza City hospitals.
Methodology: This prospective descriptive study was carried out in (NICU) in Al-Nasser and Al- Shifa hospitals in Gaza City, between January 2004 to January 2005. The patients were categorized into two groups of early and late onset septicemia.
Results: Three hundred twenty eight neonates out of 2487 cases had positive blood cultures with infection rate of 13.2%. The most common isolated pathogens were Coagulase negative Staphylococci, E. coli, and Klebsiella spp. These isolates were most sensitive to meropenem, amikacin, vancomycin, chloramphenicol, ciprofloxacine and third generation cephalosporine. The highest percentages of isolated pathogens were obtained from Al- Nasser hospital with infection rate of 52.9% for early onset sepsis and 84.5% for late respectively. While in Al-Shifa hospital the rate of early onset sepsis was 47.1% and 15.5% for late onset sepsis respectively.
Conclusion: There is a difference between the types of septicemia found in two hospitals (early onset and lately onset septicemia) with a prevalence of Coagulase negative staphylococci (57.3%), E. coli (10.4%), Klebsiella spp. (8.0%) and others (24.3%). The most effective antibiotic for Gram negative isolates was meropenem, while the most effective antibiotic for Gram positive isolates was vancomycin.
KEY WORDS: Septicemia, Neonates, Early Onset Sepsis, Late Onset Sepsis, Antimicrobial activity.
Pak J Med Sci April - June 2009 Vol. 25 No. 2 226-231
How to cite this article:
El-Jadba AHE, El-Yazji MS. Neonatal Septicemia In Gaza City Hospitals. Pak J Med Sci 2009;25(2):226-231.
1. Abed El Hakeem Noman El Jadba,
Al Dora Pediatric Hospital,
Gaza, Palestine.
2. Mansour Sobhi El Yazji,
Biology department,
Al-Aqsa University,
Gaza,
Palestine
Correspondence
Mansour Sobhi El Yazji,
E-mail: mansourelyazji@yahoo.com
Received for Publication: August 19, 2008
Revision Received: December 1, 2008
Final Revision Received January 29, 2009
Final Revision Accepted: January 31, 2009
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