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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 26 |
April - June 2010 |
Number 2 |
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Effects of sodium nitrite-induced hypoxia on
cerebellar Purkinje cells in adult ratsZeenat F. Zaidi
ABSTRACT
Objectives: To explore the changes in Purkinje cells in adult rats after inducing chemical hypoxia by sodium nitrite
Methodology: Adult male albino rats, weighing 180-200 gm were used in this study. The animals were fasted for three hours prior to drugs administration. One hour after sodium nitrite (75 mg/kg) subcutaneous injection, rats were decapitated. The brains were removed and placed overnight in fixative containing 10% formalin. Cerebellum were