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Volume 23 |
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Number 1 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 23 |
January - March 2007 |
Number 1 |
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Henna – Induced Severe Hemolysis:
In Glucose 6 – Phosphate Dehydrogenase DeficiencyAbolhassan Seyedzadeh1, Mitra Hemmati2, Simin Gheiny3
ABSTRACT
Glucose– 6–phosphate dehydrogenase deficiency is one of the most common enzyme deficiencies worldwide. Lawsone is a chemical present in henna, the crushed leaves of which are not only used as a cosmetic agent but also as a therapeutic agent for some types of skin lesion. In vitro observations indicated that lawsone is an agent capable of causing oxidative hemolysis. We report a 42 – days old G6PD – deficient male infant with acute severe hemolysis after application of henna to treat his napkin dermatitis.
KEY WORDS: Acute hemolysis, Henna, Lawsone, Glucose –6– phosphate dehydrogenase deficiency.
Pak J Med Sci January - March 2007 Vol. 23 No.1 119-121
1. Dr. Abolhassan Seyedzadeh
2. Dr. Mitra Hemmati
3. Dr. Simin Gheiny1-3: Assistant Professor of Pediatrics,
Department of Pediatrics,
Kermanshah University of Medical Sciences,
Kermanshah,
Iran.Correspondences:
Dr. Abolhassan Seyedzadeh,
Pediatrics Ward,
Imam Reza General Hospital,
Kermanshah,
Iran.
Email: aseyedzadeh2001@yahoo.com* Received for Publication: March 25, 2006
* Accepted: September 14, 2006
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