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Volume 26 |
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Number 1 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 26 |
January - March 2010 |
Number 1 |
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Pancytopenia: Megaloblastic anemia
is still the commonest causeTariq Aziz1, Liaquat Ali2, Tahir Ansari3,
Hammad Bin Liaquat4, Shahnaz Shah5, Jamal Ara6ABSTRACT
Objectives: To find out the frequency of the different causes of Pancytopenia and also to specifically detect the percentage of vitamin B12 deficieny amongst these patients.
Methodology: It is a prospective study carried out in Medical Unit I (Ward 5) of Jinnah Postgraduate Medical Centre Karachi from March to August 2007. A total of 88 patients were included after a detailed history and examinations the information was recorded on Proforma. Findings of aspiration and trephine biopsies were interpreted in the light of history, clinical examination and peripheral blood findings.
Results: Out of 88 patients suffering from Pancytopenia, a large number (40.90%) were diagnosed as Megaloblastic Anemia, out of which 77.77 % had vitamin B12 deficiency. Aplastic anemia was found in 28 (31.88%) patients followed by other less common causes.
Conclusion: Megaloblastic anemia was found in largest number of patients who were found to have Pancytopenia on initial investigations and majority of such patients were found to be deficient in Vitamin B12.
KEY WORDS:
Pancytopenia, Megaloblastic Anemia, Vitamin B12 deficiency.Pak J Med Sci January - March 2010 Vol. 26 No. 1 132-136
How to cite this article:
Aziz T, Ali L, Ansari T, Liaquat HB, Shah S, Ara J. Pancytopenia: Megaloblastic anemia is still the commonest cause. Pak J Med Sci 2010;26(1):132-136
1. Dr. Tariq Aziz, FCPS
Senior Registrar,
2. Dr. Liaquat Ali, FCPS
Associate Professor,
3. Dr. Tahir Ansari, FCPS
Senior Registrar,
4. Dr. Hammad Bin Liaquat, MBBS
House Officer/Intern
5. Dr. Shahnaz Shah, FCPS
Senior Registrar,
6. Dr. Jamal Ara, FCPS
Professor of Medicine & In charge,
1-6: Ward-5 (Medical Unit-I),
Department of Medicine,
Jinnah Postgraduate Medical Centre (JPMC),
Karachi - 75500, Pakistan.
Correspondence
Dr. Tariq Aziz, FCPS
E-mail: liaquat.ali1953@yahoo.com
* Received for Publication: July 24, 2009
* Revision Received: November 12, 2009
* Revision Accepted: November 13, 2009
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