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Volume 22 |
July - September 2006 |
Number 3 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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CASE REPORT |
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Volume 22 |
July - September 2006 |
Number 3 |
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Proptosis and Blindness: An Unusual Primary
Presentation of Chronic Granulocytic LeukaemiaMathew Ebose Enosolease, Augustina Omolade Awodu
ABSTRACT
Proptosis and blindness are uncommon presentations of chronic granulocytic leukaemia. We present a 20-year old man with four months history of bilateral swelling of the eyes and deteriorating vision, abdominal swelling and early satiety. Examination revealed massive splenomegaly and bilateral blindness resulting from retinal detachment most probably due to retro-orbital accumulation of malignant myeloid cells. Peripheral blood film confirmed chronic granulocytic leukaemia, CGL. Clinical response to hydroxyurea was excellent but retinal detachment and blindness persisted. We suggest that CGL should be excluded in all cases of painless eye-swelling.
Key words: Proptosis, Blindness, Chronic granulocytic, Leukaemia.
Pak J Med Sci July - September 2006 Vol. 22 No. 3 326-328
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