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Volume 25 |
July - September 2009 |
Number 4 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 25 |
July - September 2009 |
Number 4 |
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Vitamin-D status in a Population of
healthy adults in Pakistan
Khalid Mahmood1, Syed Tehseen Akhtar2, Abu Talib3, Iftikhar Haider4
ABSTRACT
Objective: To determine the prevalence of hypovitaminosis D and its predictors in healthy adult Pakistanis. This study was conducted at various hospitals in Karachi from April 2007 to September 2007.
Methodology: In this study 244 healthy adults 16-62 years of age, visited hospital as an attendant of the patients and fulfilled the inclusion and exclusion criteria has been enrolled. After taking written consent a questionnaire regarding age, gender, occupation, duration of sun exposure, area of skin exposed, type of residence used, clothing and dietary habits were recorded. Serum 25-OH Vitamin D3 levels were determined by electrochemiluminescence method and Vitamin D deficiency was defined as a level <20µg/ml. serum calcium. Phosphorus and Alkaline Phosphatase were also measured in all of these subjects.
Results: Among 244 subjects ranging from 16-62 years, 193(79%) were female. Subjects were predominantly married (72%), mostly residing in apartments (47.5%) and most of them (41.8%) only exposed their face and hands while outdoor. Duration of sun exposure in majority was 1-2 hour /day (42%). Majority used clothes of variable colour (72%) and fabric (41%). One hundred and eighty six (76.2%) subjects had deficiency of Vitamin D and significantly correlated with duration of sunlight exposure, large area of skin exposed, vitamin D in diet consumed and colour of clothes worn. Vitamin D was significantly correlated negatively with serum Phosphorus and Alkaline Phosphatase whereas serum calcium correlated positively.
Conclusion: Prevalence of hypovitaminosis D among healthy Pakistanis is high and duration of sun exposure is the most common predictor of hypovitaminosis D.
KEY WORDS:
Hypovitaminosis D, Healthy subjects, Risk factors.Pak J Med Sci July - September 2009 Vol. 25 No. 4 545-550
How to cite this article:
Mahmood K, Akhtar ST, Talib A,Haider I. Vitamin-D status in a Population of Healthy Adults in Pakistan. Pak J Med Sci 2009;25(4):545-550.
1. Prof Khalid Mehmood
Prof of Medicine
2. Dr.Syed Tehseen Akhtar
Senior Registrar Medical Unit IV
3. Dr. Abu Talib
Associate Prof of Medicine
4. Dr.Iftikhar Haider
Assistant Prof of Medicine
1-4: Medical Unit IV
Dow University of Health Sciences,
Karachi – Pakistan.
Correspondence
Dr. Syed Tehseen Akhtar
E-mail: drstakhtar@yahoo.com
* Received for Publication: March 17, 2009
* Accepted: July 16, 2009
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