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Volume 26 |
July - September 2010 |
Number 3 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 26 |
July - September 2010 |
Number 3 |
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Association of increased triglyceride levels in
metabolic syndrome with coronary artery diseaseMehmet Rami Helvaci1, Hasan Kaya2, Mehmet Gundogdu3
ABSTRACT
Objective: We tried to understand significance of increased triglyceride (TG) values in metabolic syndrome and coronary artery disease (CAD).
Methodology: Check up cases with a TG value lower than 60 mg/dL were collected into the first, between 60 and 99 mg/dL into the second, between 100 and 149 mg/dL into the third, between 150 and 199 into the fourth, and 200 mg/dL and greater into the fifth groups.
Results: Study included 478 cases. Values of the mean age, weight, body mass index, TG, and low density lipoprotein cholesterol (LDL-C) and prevalences of smoking, white coat hypertension (WCH), hypertension (HT), type 2 diabetes mellitus (DM), and CAD increased gradually and significantly nearly in all steps from the first towards the fifth groups.
Conclusion: Metabolic syndrome may be a progression step between complete physical health and irreversible end points, such as obesity, type 2 DM, HT, CAD, and stroke. Hypertriglyceridemia and White Coat Hypertension (WCH) may be the most significant reversible parameters of the syndrome, and it is better to have the lowest TG value as much as possible. The most significant increase was seen after the value of 100 mg/dL. The overweight, smoking, hypertriglyceridemia, hyperbetalipoproteinemia, and WCH may only be one of hundreds of parameters of the syndrome. Therefore, it is advisable that underlying etiologies rather than revesible parameters of the syndrome should be targeted for treatment. For example, increased TG and LDL-C values, and prevalence of WCH by aging may be secondary to decreased physical and mental stresses in elderly.
KEY WORDS:
Triglyceride, White coat hypertension, Metabolic syndrome.Pak J Med Sci July - September 2010 Vol. 26 No. 3 667-672
How to cite this article:
Helvaci MR, Kaya H, Gundogdu M. Association of increased triglyceride levels in metabolic syndrome with coronary artery disease. Pak J Med Sci 2010;26(3):667-672
1. Mehmet Rami Helvaci, MD,
Associated Professor of Internal Medicine,
2. Hasan Kaya, MD,
Professor of Internal Medicine,
3. Mehmet Gundogdu, MD,
Prof. of Internal Medicine, Medical Faculty of the
Ataturk University, Erzurum, Turkey.
1-2: Medical Faculty of the Mustafa Kemal University,
31100, Serinyol, Antakya, Turkey.
Correspondence:
Mehmet Rami Helvaci, MD,
E-mail: mramihelvaci@windowslive.com
* Received for Publication: October 7, 2009
* Revision Received: October 28, 2009
* Second Revision Received: June 1, 2010
* Final Revision Accepted: June 2, 2010
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