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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 25 |
October - December 2009 (Part-I) |
Number 5 |
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Seroprevalence of Legionella pneumophila in admitted
patients with pneumonia in training hospitals, Ahvaz, Iran
Seyed Mohammad Alavi1, Naser Moshiri2,
Moosavian M3, Yusefi F4, Abbasi E5
ABSTRACT
Objectives: To determine the seroprevalence of Legionella pneumophila (LP) in patients with pneumonia.
Methodology: During a 12-month study period, from December 2007 and November 2008 121 randomized selected patients admitted to the three training hospitals of Jundishapoor University of Medical Science in Ahvaz (a city southwest Iran) with pneumonia were investigated to determine the serprevalence of LP. The diagnosis of LP infection was based on positive serology. Sera were tested for L. pneumophila IgG and IgM by using Elisa kit (Vircell, Spain). All analyses were done using the SPSS, version 16 statistical package.
Results: Of a total of 121 serum samples tested, 21 (17.3%) were positive for LP- IgG, IgM. Fifty percent of pneumonia patients in ICU were seropositive. Age, gender and area of residency did not significantly (p >0.05) affect the seroprevalence of LP. Overall, the prevalence of LP seropositivity was not significantly (p >0.05) affected by co-morbidities except diabetes melitus. Smoking and receiving antibiotic was observed in 86% and 100% seropositve patients.
Conclusion: Legionella pneumophila is a prevalent infectious agent in the region of study and should be considered as potential invader patients with pneumonia especially in diabetic, smoker and ICU patients.
KEYWORDS:
Legionella pneumophila, Pneumonia, Seroprevalence, Ahvaz.Pak J Med Sci October - December 2009 (Part-I) Vol. 25 No. 5 811-816
How to cite this article:
Alavi SM, Moshiri N, Mmoosavian M, Yusefi F, Abbasi E. Seroprevalence of Legionella pneumophila in admitted patients with pneumonia in training hospitals, Ahvaz, Iran (2007-2008). Pak J Med Sci 2009;25(5):811-816.
1. Dr. Seyed Mohammad Alavi, MD.
Associated Professor of Medical College,
2. Dr Naser Moshiri, MD
3. Dr Mojtaba Moosavian, PhD.
Associated Professor of Medical College,
4. Dr Farid Yusefi, MD.
AssistantProfessor of Medical College,
1,2,4: Infectious disease ward,
Razi Hospital, Iran.
1-4: Joundishapour Infectious and
Tropical Diseases Research Center,
Iran.
5. Effat Abbasi, MS.
Joundishapour University of Medical Sciences,
Ahvaz, Iran,
Joundishapour Infectious Diseases and
Tropical Medicine Research Center,
Iran.
Correspondence
Dr. Seyed Mohammad Alavi, MD.
Associated Professor of Medical College,
Infectious & Tropical Diseases Research Center,
Infectious Disease Ward,
Razi Hospital, Iran.
Maling Address: No: 52,
West 11 Avenue,
Kianabad,
Ahvaz, Iran
Email:alavi1329dr@yahoo.com
* Received for Publication: March 9, 2009
* Accepted: July 25,2009