Increased heart rate on first day in Intensive Care Unitis associated with increased mortality | Kara | Pakistan Journal of Medical Sciences Old Website

Increased heart rate on first day in Intensive Care Unitis associated with increased mortality

Duygu Kara, Seda Banu Akinci, Gulcin Babaoglu, Ulku Aypar


Objective: To investigate the association of maximum HR during the first day of intensive care unit (ICU) and mortality.

Methods: Data of 850 patients over 45 years of age, who were  hospitalized in ICU, was retrospectively analyzed. They were divided into two groups; Group-I, patients with maximum HR<100/min Group-II, patients with maximum HR≥100/min on first day. The groups were compared regarding age, sex, use of beta-blockers, use of inotropic and vasopressor drugs, hemodynamic parameters, anemia, mechanical ventilation, length of hospitalization (ICU and total), mortality (ICU and total), and CHARLSON & APACHE-II scores.

Results: The mean age of patients was 63±12 years and 86% were after non-cardiac surgery. Maximum HR was 83±11 in Group-I and 115±14/min in Group-II (p=0.002). Group-II patients had more frequent vasopressor and inotropic drugs usage, (p<0.001), anemia, mechanical ventilation (p<0.005), higher CHARLSON & APACHE-II scores, stayed longer in ICU and hospital, and had higher ICU and hospital mortality compared to group-I (p<0.05). APACHE-II scores and maximum HR<100/min were independent variables predicting ICU mortality in multivariate logistic regression analysis whereas usage of beta-blockers was not.

Conclusions: Our study showed that maximum HR less than100/minute during the first day of ICU is associated with decreased mortality in Intensive Care Unit.


How to cite this:Kara D, Akinci SB, Babaoglu G, Aypar U. Increased heart rate on first  day in Intensive Care Unit is associated with increased mortality. Pak J Med Sci. 2016;32(6):1402-1407.   doi:

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