Platelet receptors: An instrumental of platelet physiology

Abstract

Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs. This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.

doi: http://dx.doi.org/10.12669/pjms.293.3497

How to cite this:Saboor M, Ayub Q, Samina Ilyas, Moinuddin. Platelet receptors: An instrumental of platelet physiology. Pak J Med Sci 2013;29(3):891-896.   doi: http://dx.doi.org/10.12669/pjms.293.3497

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.