Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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CASE REPORT

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Volume 24

April - June 2008 (Part-I)

Number  2


 

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Hashimoto’s encephalopathy:
A frequently missed diagnosis

Mohamed Osama Hegazi1, Mubarak Alajmi2, Yasser M Ateya3

ABSTRACT

Hashimoto’s encephalopathy is described as a syndrome of encephalopathy and high serum antithyroid antibodies that is responsive to glucocorticoid therapy. We report a patient with overt hypothyroidism who presented with stroke-like episodes and a status epilepticus which responded dramatically to intraveous methylprednisolone given for a severe bronchospasm following aspiration. The high antithyroid antibody titers and the response to steroids supported the diagnosis of Hashimoto’s encephalopathy. The diagnosis of Hashimoto’s encephalopathy is generally under diagnosed and often missed at presentation.

KEY WORDS: Autoimmune, Encephalopathy, Hashimoto, Thyroiditis, Steroids.

Pak J Med Sci    April - June 2008 (Part-I)    Vol. 24 No. 2    314-316


1. Mohamed Osama Hegazi, MRCP (UK),
Senior Registrar
Medical Department,
2. Mubarak Alajmi, ABIM, FRCPC,
ICU and Respirology Consultant,
Respirology Department,
3. Yasser M Ateya, MSc.
Registrar,
Medical Department,
1-3: Al Adan Hospital,
Kuwait

Correspondence

Dr. Mohamed Osama Hegazi,
P.O. Box 47813,
Fahaheel, 64029,
Kuwait.
Email: drosama02@gmail.com

* Received for Publication: November 24, 2007
* Accepted: February 15, 2008



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