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Volume 26 |
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Number 1 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 26 |
January - March 2010 |
Number 1 |
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Frequency of beta thalassemia trait
and carrier in Gorgan, IranNarges Mirbehbahani1, Azam Jahazi2,
Mohammad Reza Rabie3, Flora Vafai4ABSTRACT
Objectives: To determine the frequency of beta-Thalassemia trait and carrier in Gorgan, Iran.
Methodology: In this analytic cross sectional study conducted from March 20, 2003 until March 20, 2004, two thousands six hundred prospective grooms and brides referred to the health center of Gorgan city were studied. Globular criteria included mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV) were determined. Hemoglobin A2 (Hb A2) was measured by column chromatography method.
Results: The range of MCH was 13.8-35.5 pg. %15.9 of men and %27.6 of women had MCV<80fl. The frequency of beta-thalassemia trait was 9.8%. The range of HbA2 was 1.2-12% with the mean 3.06±1.5%. The frequency of beta-Thalassemia carrier (minor) was 21.4 %.
Conclusion: This high frequency of beta-Thalassemia trait and carrier in Gorgan constitutes a real health problem and it necessitates more diligent effort in health care specially education and counseling. Further studies should examine the value of counseling and the prevalence of beta-Thalassemia in the children of those married.
KEY WORDS: Beta-Thalassemia trait, Beta-Thalassemia carrier, Frequency.
Pak J Med Sci January - March 2010 Vol. 26 No. 1 40-42
How to cite this article:
Mirbehbahani N, Jahazi A, Rabie MR, Vafai F. Frequency of beta thalassemia trait and carrier in Gorgan, Iran. Pak J Med Sci 2010;26(1):40-42
1. Narges Mirbehbahani,
Hematologist,
Golestan University of Medical Sciences,
Gorgan, Golestan, Iran.
2. Azam Jahazi,
Master Science of Midwifery,
Islamic Azad University Gorgan Branch,
Midwifery Department, Gorgan,
Golestan, Iran.
3. Mohammad Reza Rabie,
Master Science of statistics
4. Flora Vafai,
Physician
Correspondence
Azam Jahazi,
Islamic Azad University Gorgan Branch,
Midwifery Department, Gorgan,
Golestan, Iran
E-Mail: ajahazi@gmail.com
* Received for Publication: April 20, 2009
* Revision Received: November 21, 2009
* Revision Accepted: November 26, 2009
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