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Volume 25 |
July - September 2009 |
Number 4 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 25 |
July - September 2009 |
Number 4 |
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The effects of oligofructose and polydextrose on
metabolic control parameters in Type-2 diabetes
Betul Cicek1, Perihan Arslan2, Fahrettin Kelestimur3
ABSTRACT
Objective: This study investigated the effects of oligofructose and polydextrose on metabolic control in Type-2 diabetes.
Methodology: Twenty voluntary, postmenopausal, total cholesterol (TC)/HDL-cholesterol (HDL-C) ratios >4.5, female, Type-2 diabetes patients were included. The study was performed in four periods, with the baseline as the period one. In periods two and four, the patients consumed individual diabetic diets for eight weeks. In period three, they consumed 20g of oligofructose and polydextrose mixture in 40g sweetener (in powdered form), added to their diets for six weeks.
Results: Prebiotic soluble fiber sources (oligofructose and polydextrose) significantly decreased fasting and postprandial (2-hour) blood glucose, glycosylated hemoglobin, TC, LDL-cholesterol (LDL-C), TC/HDL-C and LDL-C/HDL-C ratios, triglyceride, VLDL-cholesterol, lipoprotein (a), systolic and diastolic blood pressures (p<0.001), apolipoprotein B (p<0.05), and increased HDL-C, insulin (p<0.05), and C-peptide levels (p>0.05) compared to the initial values, respectively.
Conclusion: Individual diabetic diets supplemented with prebiotics improved metabolic control in Type-2 diabetes.
KEY WORDS: Diet, Type-2 diabetes, Nutrition, Oligofructose, Polydextrose, Prebiotics.
Pak J Med Sci July - September 2009 Vol. 25 No. 4 573-578
How to cite this article:
Cicek B, Arslan P, Kelestimur F. The effects oligofructose and polydextrose on metabolic control parameters in Type-2 diabetes. Pak J Med Sci 2009;25(4):573-578.
1. Betul Cicek, PhD,
Assist. Professor,
Department of Nutrition and Dietetics,
Erciyes University, Ataturk Health School,
Kayseri, Turkey.
2. Prof. Perihan Arslan, PhD
Department of Nutrition and Dietetics,
Faculty of Health Sciences, Hacettepe University,
Ankara, Turkey
3. Prof. Fahrettin Kelestimur, MD.,
Erciyes University, School of Medicine,
Department of Internal Medicine,
Division of Endocrinology and Metabolism,
Kayseri, Turkey.
Correspondence
Betul Cicek, PhD,
E-mail: betul.cicek@gmail.com
* Received for Publication: February 20, 2009
* Accepted: June 29, 2009
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