Systemic lupus erythematosis with severe aplastic anemia successfully treated with rituximab and antithymocyte globulin
Abstract
Hematologic disorders are very common in Systmic lupus erythematosus (SLE).First presentation of SLE with severe aplastic anemia (SAA) is extremely rare. We report a patient with the diagnosis of secondary SAA associated with SLE. Conventional therapy was not effective. She received Rituximab (RTX) and Antithymocyte globulin (ATG) therapy, her response was satisfactory finally. Her hematologic parameters were within normal ranges until last follow-up, eight months and six months after therapy was initiated with RTX and ATG, respectively. This is the first time RTX and ATG were successfully used in the treatment of SAA secondary to SLE.
doi: http://dx.doi.org/10.12669/pjms.302.4200
How to cite this:Liu W, Hu Z, Lin S, He J, Zhou Y. Systemic lupus erythematosis with severe aplastic anemia successfully treated with rituximab and antithymocyte globulin. Pak J Med Sci 2014;30(2):449-451. Â doi: http://dx.doi.org/10.12669/pjms.302.4200
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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