Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 22

October - December 2006

Number 4


 

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Peadiatric Visceral Leishmanisis in the
South West Part of Iran:
A study of 215 Cases

Ahmad Shamsizadeh1, Roya Nikfar2, Sharif Maraghi3 , Nahid Zaker4

ABSTRACT

Objective: To study the epidemiological, clinical charactristics and laboratory findings of visceral leishmaniasis (VL) in children.

Design: It is a retrospective study, hospital records of all children with diagnosis of VL were reviewed from 1991 through 2003.

Setting: Hospitals affiliated to Ahvaz Jondi-Shapour University of Medical Sciences in the southwestern part of Iran.

Subjects: Two hundreds and fifteen patients (153 males and 62 females) were enrolled in the study.

Results: The mean age of the patients was 31 ± 22 months. Fever and splenomegaly were present in >95% of the patients and hepatomegaly and lymphadenopathy in 76% and 3.7% of cases, respectively. Common laboratory findings were anemia, leukopenia and thrombocytopenia.All patients were treated with meglumine antimoniate.Relapse were observed in 4% of the patients and fatality rate was 5%.

Conclusions: Visceral leishmaniasis is endemic in the southwestern part of Iran. The clinical profile of the disease is typical of the Mediterranean infantile form.

KEY WORDS: Visceral leishmaniasis, Children, Iran.

Pak J Med Sci October - December 2006 Vol. 22 No. 4 461-464


1. Ahmad Shamsizadeh
Assistant Professor of Pediatric Infectious Diseases

2. Roya Nikfar
Assistant Professor of Pediatric Infectious Disease

3. Sharif Maraghi
Professor of Parasitology
Department of Mycoparasitology,
School of Medicine,

4. Nahid Zaker
Assistant Professor of Pediatric Infectious Diseases

1-4: Infectious and Tropical Diseases Research Center,
Ahvaz Jondi-Shapour University of Medical Sciences,
Ahvaz, Iran.

Correspondence:
Dr. Ahmad Shamsizadeh
Email: shamsizadeh@ajums.ac.ir

* Received for Publication: September 30, 2005

* Accepted: May 15, 2006


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